Technology

Our Technology

Bio-Stream has developed an integrated diagnostic testing platform that uses organic electro-chemical transistor (OECT) technology.

  • Efficient ion to electron transducer generates detectable voltage signal 
  • Results returned in minutes 
  • Very high sensitivity and specificity at low levels of detection
  • Different tests possible by simply swapping the chemistry
  • Disposable low cost test strips and a low cost reusable Bluetooth enabled reader
  • Powered by proprietary algorithms
  • Architected on APIs allowing seamless data integration
  • Data is captured on a trusted server 
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OECT Test Strip and Reader

A significant barrier to early disease treatment is waiting for diagnostic test results to come back from the lab. It is for this reason that testing has had only limited value in stopping the transmission of COVID-19. Bio-Stream understands that the pandemic is not over. The first product developed is a point-of-care test for the SARS-CoV-2 virus that can deliver immediate results at accuracy levels comparable to PCR testing, even when a persons viral load is still very low. This test will revolutionize COVID-19 detection.

Bio-Stream’s testing technology is based on an organic electro-chemical transistor platform (OECT). The intimate contact between the analyte and the electrodes allows instant signal generation. The algorithms built into the reader allows for digital detection of significantly weaker voltage shifts generated from samples with low viral concentration. This means that the Bio-Stream OECT test has lower limits of detection making it highly  sensitive, and that the interpretation of the results is quantitative rather than qualitative, making result interpretation automated, consistent and accurate.

The beauty is that an OECT transistor can be functionalized with different kinds of bait such as antibodies, aptamers and chemicals.  This means that by simply changing the functionalization chemistry, another type of test can be developed using the same OECT strip technology and reader.  This opens up opportunities to develop hundreds of applications not only for healthcare but also a range of other uses in animal health, agriculture, the military, and environmental monitoring. 

The Bio-Stream OECT testing platform is distinguished by its critical combination of: 

Speed
Affordability
Accuracy
Simplicity of use at Point-of-Care
Versatility